Fig. 2

Timeline and experimental design of the study. The cats in the ∆gIgE, ΔTK, and ΔgIgE/TK groups were intranasally inoculated with the FHV ΔgIgE eGFP, FHV ΔTK mCherry, and FHV ΔgIgE/TK eGFP-mCherry mutants, respectively, on days 0 and 28, followed by subcutaneous inoculation with the respective mutant on day 28. The control group was not inoculated. All four groups were challenged intranasally with virulent FHV WX19 (CH) on day 49