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Fig. 2 | Virology Journal

Fig. 2

From: Differential abundance of IgG antibodies against the spike protein of SARS-CoV-2 and seasonal coronaviruses in patients with fatal COVID-19

Fig. 2

Simple and multiple linear regression analysis of Betacoronavirus spike IgG titers and VNT. A Q-Q plot of residuals of log-transformed titer data to assess normality. Data passed the normality test (D’agostino-Pearson Omnibus test, P = 0.01). B Simple linear regression to estimate the relationship between SARS-CoV-2 spike IgG and the virus neutralization titer (VNT). C same as (B) but for OC-43 spike IgG D same as (B) but for HKU1 spike IgG. E Main effects model the of Betacoronavirus (SARS-CoV-2, OC43, HKU1) spike IgG titers and SARS-CoV-2 virus neutralization (VNT). Models with and without potential interaction were analyzed (only interactions between eCoV-spike and SARS-CoV-2 on VNT). Regression formula for models with and without assumed interactions are shown below. F Tabular results of the statistics: SARS-CoV-2 IgG titer was a strong predictor of VNT, and no significant effect of the other variables on VNT could be shown. Significant values are denoted in bold in the table

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Virology Journal

ISSN: 1743-422X