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Fig. 2 | Virology Journal

Fig. 2

From: Peripheral blood lymphocytes influence human papillomavirus infection and clearance: a retrospective cohort study

Fig. 2

The association between peripheral blood lymphocyte subset percentages and different types of HPV infection (VS uninfected) at baseline. The percentages of B cells, T cells, CD4 + T cells, CD8 + T cells and NK cells as well as the CD4/CD8 ratio were dichotomized according to the median value. Odds ratios were adjusted for age and gravidity. The blue lines indicate that the difference was meaningful (P < 0.05), while the black lines indicate that the difference was not significant (P > 0.05). Low CD4 + T-cell percentages often facilitate HPV (OR 1.58, 95% CI 1.16–2.15, P<0.05), HR-HPV (OR 1.71, 95% CI 1.23–2.36, P<0.05), HPV18 (OR 2.37, 95% CI 1.12–5.02, P<0.05) and HPV52 infections (OR 3.67, 95% CI 1.78–7.54, P<0.05), while low CD4/CD8 ratios facilitate HPV (OR 1.42, 95% CI 1.04–1.94, P<0.05), HR-HPV (OR 1.48, 95% CI 1.07–2.05, P<0.05) and HPV52 infections (OR 3.39, 95% CI 1.65-7.00, P<0.05). HR-HPV: High-risk HPV including HPV-16, -18, -31, -33, -35, -39, -45, -51, -52, -56, -58, -59, -66, -68; LR-HPV: Low-risk HPV including HPV-6, -11, -42, -43, -81; OHR-HPV: Other high-risk HPV including HPV-31, -33, -35, -39, -45, -51, -59, -66, -68; OR: Odd Ratio

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