Fig. 3
From: Cutavirus on the skin in an Asian cohort: identification of a novel geographically related genotype
Phylogenetic trees generated using the maximum-likelihood method. (A) A phylogenetic tree was constructed based on 40 near-full-length cutavirus (CuV) sequences (4455 bp). These included 36 sequences that were successfully amplified from skin swab specimens from the Japanese individuals included in this study and four sequences retrieved from GenBank. The two major nucleotype clades (clades 1 and 2) are indicated. (B) A phylogenetic tree was constructed based on 55 CuV viral capsid protein 1 (VP1)/VP2 sequences with 538 bp (nucleotide positions 3778–4315 bp). These included the 36 sequences from the Japanese individuals and 19 sequences recovered from individuals of various geographic origins that were retrieved from GenBank as of December 1, 2022. The CuV reference sequence of the BR-337 strain (GenBank accession number no., NC_039050) is indicated with an asterisk. The sequences obtained from the Japanese individuals in the present study are presented in bold and colored in red. The CuV strains from Brazil, Botswana, and Europe are colored green, purple, and blue, respectively. The Brazilian and Botswanan strains were from fecal specimens, whereas the remaining strains were from skin specimens. The names of the sequences are indicated together with the GenBank accession numbers and country of origin in parentheses. The percentage bootstrap values calculated from 1000 replicates are indicated at the internal nodes. The scale bars represent the number of substitutions per site