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Fig. 10 | Virology Journal

Fig. 10

From: ARIH1 inhibits influenza A virus replication and facilitates RIG-I dependent immune signaling by interacting with SQSTM1/p62

Fig. 10

Schematic of ARIH1 action on innate immune signaling pathway. Influenza A virus infection activates RIG-I signaling, which is regulated by a variety of host factors. ARIH1 is up-regulated by influenza A virus and can antagonize the SQSTM1/p62-induced degradation of RIG-I by interacting with SQSTM1 and blocking its binding to RIG-I to promote interferon production

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Virology Journal

ISSN: 1743-422X