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Fig. 5 | Virology Journal

Fig. 5

From: The persistence and stabilization of auxiliary genes in the human skin virome

Fig. 5

Erm(C) variant phylogeny (unscaled) shows a high abundance of only functional versions of erm(C) across subjects. Protein folding structural damage and deleterious effects from mutagenesis within the sampling population were predicted using the protein variant structural effect prediction tools PROVEAN, SIFT, and Missense-3D [49,50,51]. Squares to the right of the variant id (i.e., ASV ##) indicate the presence of a negative impact on protein functionality via either deleterious mutagenesis (black square) or structural damage (red square). A heatmap representing total abundance for each erm(C) sequence variant by subject was also provided. Only variants that did not exhibit deleterious or structural damage due to mutagenesis displayed high abundance across subjects

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