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Table 3 Estimates of diagnostic accuracy and their precision (such as 95% confidence intervals)

From: Evaluation of ten (10) SARS-CoV-2 rapid serological tests in comparison with WANTAI SARS-CoV-2 ab ELISA in Burkina Faso, West Africa

 

COVID-19 IgG/IgM Rapid

Test

Sienna TM

COVID-19IgG/IgM Rapid

Test

Biosynex

COVID-19 IgG/IgM

Cassette

ACCU-Tell

COVID-19 IgG/IgM

Rapid Test InnoScreen™

COVID-19 IgG/IgM

Rapid test Device WB/S/P

Safecare Bio-Tech

Parameters

Estimate

95%CI

Estimate

95%CI

Estimate

Estimate

Estimate

95%CI

Estimate

95%CI

Sensitivity (%)

45.22

37.64–53.03

48.41

40.72–56.17

39.49

39.49

49.04

41.34–56.79

39.49

32.18–47.3

Specificity (%)

98.09

94.53–99.35

99.36

96.48–99.89

98.09

98.09

97.45

93.63-99.0

98.09

94.53–99.35

PPV (%)

95.95

88.75–98.61

98.7

93,0-99.77

95.38

95.38

95.06

87.98–98.06

95.38

87.29–98.42

NPV (%)

64.17

57.92–69.97

65.82

59.57–71.57

61.85

61.85

65.67

59.36–71.46

61.85

55.68–67.66

PLR

23.67

11.91–47.03

76.0

10.42–55.46

20.67

20.67

19.25

11.49–32.26

20.67

10.24–41.69

NLR

0.56

0.54–0.57

0.52

0.51–0.53

0.62

0.62

0.52

0.51–0.53

0.62

0.60–0.63

Kappa

0.4331

0.34–0.52

0.48

0.38–0.57

0.37

0.37

0.46

0.37–0.56

0.37

0.29–0.46

Accuracy (%)

71.66

66.43–76.36

73.89

68.76–78.43

68.79

68.79

73.25

68.09–77.84

68.79

63.46–73.66

 

COVID-19 IgG/IgM Rapid

Test Whole

blood/Serum/Plasma

2019-nCOV IgG/IgM Rapid

test Device

Hangzhou Realy Tech

COVID-19 IgG/IgM Rapid

Test (Zhejiang Orient Gene

Biotech Co.-Ltd)

STANDARD Q COVID-19

IgM/IgG Combo

SD Biosensor

Panbio COVID-19 IgG/IgM

Rapid test Device

Abbott

Parameters

Estimate

95%CI

Estimate

95%CI

Estimate

95%CI

Estimate

95%CI

Estimate

95%CI

Sensitivity (%)

49.04

41.34–56.79

27.39

21.02–34.84

51.59

43.83–59.28

61.67

49.02–72.91

40

28.57–52.63

Specificity (%)

99.36

96.48–99.89

98.09

94.53–99.35

97.45

93.63-99

100

93.98–100

93.33

84.07–97.38

PPV (%)

98.72

93.09–99.77

93.48

82.5- 97.76

95.29

88.52–98.16

100

90.59–100

85.71

68.51–94.3

NPV (%)

66.1

59.85–71.84

57.46

51.48–63.24

66.81

60.48–72.59

72.29

61.84–80.77

60.87

50.65–70.21

PLR

77.0

10.56–561.3

14.33

6.61–31.09

20.25

12.13–33.81

Undefined

undefined’.

6.0

3.25–11.07

NLR

0.51

0.50–0.52

0.74

0.73–0.75

0.50

0.48–0.51

0.38

0.35–0.41

0.64

0.61–0.68

Kappa

0.48

0.39–0.58

0.25

0.18–0.33

0.49

0.39–0.59

0.62

0.45–0.78

0.33

0.18–0.48

Accuracy (%)

74.2

69.09–78.73

62.74

57.27–67.9

74.52

69.43–79.03

80.83

72.88–86.88

66.67

57.83–74.47

  1. Legend: Se: Sensitivity, Sp: Specificity, PPV: positive predictive value, NPV = negative predictive value, PLR: positive likelihood ratio, NLR: negative likelihood ratio.