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Fig. 6 | Virology Journal

Fig. 6

From: IL-17A plays a critical role in RSV infection in children and mice

Fig. 6

IL-6 / IL-21 -IL-23R- RORγt signaling pathway is elevated during RSV infection. IL-6 / IL-21 -IL-23R- RORγt signaling pathway is involved in regulating IL-17A in other models [12]. We thus detected this pathway in our study. A IL-6 levels in BALF. B IL-21 levels in BALF. C IL-23 levels in BALF. D Gene expression of IL-23R. E Gene expression of the transcription factor RORγt. Graphs are represented as the mean±s.e.m. Data are representative of two independent experiments performed on 6 animals per group. *P < 0.05, **P < 0.01, ***P < 0.001 shown comparing the RSV group with the control group

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