Skip to main content
Fig. 4 | Virology Journal

Fig. 4

From: IL-17A plays a critical role in RSV infection in children and mice

Fig. 4

RSV-associated airway inflammation and AHR were decreased in IL-17A-/- mice. Wild-type C57BL/6 mice and IL-17A-/- mice (on C57BL/6 background) were sacrificed on day 21 after inoculation with RSV. A Total inflammatory cells isolated from BALF. B AHR in response to increasing doses of methacholine. C Representative HE staining and HPS of lung tissue sections (original Magnification × 200). a: control wild type mice; b: RSV-infected wild type mice; c: control IL-17A-/- mice; d: RSV-infected IL-17A-/- mice; e: HPS. Graphs are represented as the mean±sem. Data are representative of two independent experiments performed on 6 animals per group. **P < 0.01, ***P < 0.001 shown comparing the control group with the RSV group in wild type mice; ^P < 0.05, ^^^P < 0.001 shown comparing the control group with the RSV group in IL-17A-/- mice; + P < 0.05, + +P < 0.01, +++P < 0.001 shown comparing the wild type mice with the IL-17A-/- mice

Back to article page