Fig. 3

Anti-HSV-1 effect of AEE on neuronal cells. A and B U87-MG cells were infected with HSV-1 (MOI = 0.1) in the presence of AEE (10 μg/ml) for 24 h, and total DNA or RNA was extracted. The DNA copy numbers (A) or the mRNA expression levels (B) of viral genes were analyzed by RT-qPCR. C SH-SY5Y cells were infected with HSV-1 (MOI = 0.1) in the presence of AEE (10 μg/ml) for 24 h, and the DNA copy numbers of viral genes were determined by RT-qPCR. Data were presented as the means ± SD (n = 3). *P < 0.05, **P < 0.01, ***P < 0.001 versus HSV-1-treated group, unpaired t test