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Table 5 Predictive value of various noninvasive methods to identify histological indication for antiviral therapy in training cohort

From: A noninvasive model discriminating significant histological changes in treatment-naive chronic hepatitis B patients with normal ALT

 

AUROC

95%CI

APRI

0.631

0.561–0.687

FIB-4

0.623

0.567–0.691

ALT

0.762

0.709–0.814

LS

0.795

0.760–0.852

Age

0.585

0.520–0.650

PLT

0.561

0.532–0.607

AAPL model

0.851

0.814–0.894

  1. CHB chronic hepatitis B, APRI aspartate aminotransferase to platelet ratio index, FIB-4 fibrosis index based on the four factors, ALT alanine transaminase, LS liver stiffness, PLT platelet, AUROC area under the receiver operator characteristic curve, CI confidence interval