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Fig. 1 | Virology Journal

Fig. 1

From: Highly efficacious and safe neutralizing DNA aptamer of SARS-CoV-2 as an emerging therapy for COVID-19 disease

Fig. 1

AYA2012004_L specifically neutralizes S protein VLP uptake by hACE2 transgenic mice lung cells. A Schematic experimental design of mice treatment conditions. B A representative FACS plot showing the neutralization effect of AYA2012004_L on S protein VLP uptake by lung cells. Cells were gated based on DPBS treated control group. C Percent uptake of S protein VLP by lung cells. Uptake of VLPs by lung cells was calculated according to the formula: [(frequency of GFP+ cells of test group − frequency of GFP+ cells of control group)/(frequency of GFP+ cells of VLPs treated group − frequency of GFP+ cells of control group)] \(\times\) 100. Individual dots represent data generated with cells from different mice. Data are expressed as mean ± SD. The p values were determined with unpaired Student t test. **** denotes p\(<0.0001\)

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