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Table 1 EBV type association with unique recombination events

From: Profiling genome-wide recombination in Epstein Barr virus reveals type-specific patterns and associations with endemic-Burkitt lymphoma

Recombination event

CDS cut by start breakpoint

CDS cut by end breakpoint

Frequency in type 1 (%)

Frequency in type 2 (%)

p value

21

BORF1, BORF2

BRLF1

0/56 (0)

20/30 (63)

8.97e − 10

28

BRLF1

BKRF2

11/56 (20)

0/30 (0)

0.01

37

EBNA3B

BGLF1, BGLF4

9/56 (16)

0/30 (0)

0.02

38

BNRF1

BOLF1, BPLF1

9/56 (16)

0/30 (0)

0.02

47

BRLF1, BZLF1

BDLF3.5, BDLF4

22/56 (39)

0/30 (0)

0.002

50

LMP2A, LMP2B

EBNA2

20/56 (36)

0/30 (0)

0.0001

  1. eBL endemic Burkitt lymphoma, CDS coding sequence
  2. Bold text indicates a statistically significant difference with a p value < 0.05. All groups’ proportions were compared using Fisher’s exact test