Table 2 Trained immunity in cancer
From: The mechanisms and cross-protection of trained innate immunity
Stimulant | Cancer | Study type | References |
|---|---|---|---|
BCG vaccine | Bladder cancer | Meta-Analysis | [138] |
Melanoma | Randomized controlled trial | [139] | |
Lymphoma | Retrospective control study | [121] | |
Acute myelogenous leukemia | Randomized controlled trial | [122] | |
Breast cancer | SCID mice | [124] | |
Liver cancer | Guinea pigs | [21] | |
Prostatic cancer | Randomized controlled trial | [117] | |
Gastric cancer | Randomized controlled trial | [118] | |
Colon cancer | BALB/c mice | [119] | |
Lung cancer | Randomized controlled trial | [140] | |
Head and neck squamous cell Carcinoma | In vitro | [120] | |
Imiquimod | Basal cell carcinoma | Randomized controlled trial | [141] |
Coley’s toxin | Sarcoma | Randomized controlled trial | [142] |
Influenza virus | Lung cancer | BALB/c mice | [113] |
β-Glucan | Lung cancer | C57BL/6 J mice | [130] |
Lymphoma | Randomized controlled trial | [136] | |
Myelodysplastic syndrome | Randomized controlled trial | [131] | |
Breast cancer | Randomized controlled trial | [132] | |
Colorectal cancer | Randomized controlled trial | [137] | |
Ovarian cancer | Randomized controlled trial | [143] | |
Non-small-cell lung cancer | Randomized controlled trial | [133] | |
Colorectal cancer | Phase II, Randomized controlled trial | [134] | |
Acute lymphoid leukemia | BN/RijHsd rats | [135] | |
Cervical cancer | Retrospective case–control study | [144] |