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Fig. 13 | Virology Journal

Fig. 13

From: Mechanism of autophagy induced by activation of the AMPK/ERK/mTOR signaling pathway after TRIM22-mediated DENV-2 infection of HUVECs

Fig. 13

Effect of TRIM22 knockdown on autophagy-related factors. A The effect of TRIM22 knockdown on autophagy-related factors in DENV-2-infected HUVECs as detected by western blot analysis; B–G The quantitative expressions analysis autophagy-related proteins. shCtrl group: DENV-2 + shCtrl group; shTRIM22 group: DENV-2 + shTRIM22 group; AICAR group: DENV-2 + shCtrl + AICAR group; shTRIM22 + AICAR group: DENV-2 + TRIM22 + AICAR group. *represents comparison with the shCtrl group; *P < 0.05, **P < 0.01, and ***P < 0.001. #represents comparison with the shTRIM22 + AICAR group; #P < 0.05, ##P < 0.01, and ###P < 0.001

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Virology Journal

ISSN: 1743-422X