Table 1 Polyclonal sera screens using the CHIKV anti-budding assay
From: A high-throughput screening assay to identify inhibitory antibodies targeting alphavirus release
Sample ID | DPO | % No antibody control | RT-PCR | IgM | IgG | CHIKV status | |
|---|---|---|---|---|---|---|---|
1:100 | 1:1000 | ||||||
TT002a | 200 | 3.55 | 7.09 | + (3 dpo) | − | + | Recovered |
TT002b | 640 | 5.46 | 10.50 | + (3 dpo) | − | + | Recovered |
TT003 | 262 | 12.45 | 34.00 | + (4 dpo) | − | + | Recovered |
TT009 | 182 | 17.94 | 19.67 | + (7 dpo) | + | + | Recovered |
TT010 | 332 | 84.79 | 87.52 | − (4 dpo) | ± | + | Recovered |
TT015a | 3 | 80.93 | 98.08 | − | − | − | Acute |
TT015b | 141 | 20.96 | 32.59 | − (3 dpo) | + | + | Recovered |
TT016a | 3 | 70.18 | 88.52 | + | + | − | Acute |
TT016b | 128 | 16.77 | 15.36 | + (3 dpo) | ± | + | Recovered |
TT018 | 4 | 38.33 | 73.85 | + | − | − | Acute |
TT024 | 240 | 2.00 | 5.97 | N/A | − | + | Recovered |
TT030 | 150 | 32.69 | 16.73 | N/A | − | + | Recovered |
TT032 | 210 | 3.33 | 10.14 | N/A | + | − | Recovered |
TT035a | 135 | 20.77 | 15.57 | N/A | − | + | Recovered |
TT035b | 302 | 29.89 | 23.42 | N/A | − | + | Recovered |
TT037 | 210 | 20.14 | 10.00 | N/A | + | + | Recovered |
TT038a | 210 | 26.98 | 11.10 | N/A | − | + | Recovered |
TT038b | 952 | 32.98 | 24.37 | N/A | − | + | Recovered |
TT039 | 655 | 28.70 | 66.26 | N/A | − | + | Recovered |
TT046 | 210 | 38.78 | 71.38 | N/A | − | + | Recovered |
TT047a | 45 | 8.16 | 11.56 | N/A | + | + | Recovered |
TT047b | 130 | 5.00 | 10.00 | N/A | + | + | Recovered |
TT052 | 360 | 6.29 | 16.27 | N/A | ± | + | Recovered |
TT054 | 330 | 2.96 | 9.98 | N/A | ± | + | Recovered |
TT059a | 10 | 15.11 | 19.87 | − | + | ± | Acute |
TT059b | 145 | 5.81 | 15.28 | − (10 dpo) | − | + | Recovered |
TT059c | 284 | 17.47 | 12.61 | − (10 dpo) | − | + | Recovered |
TT065 | 13 | 29.41 | 72.01 | − | − | + | Recovered |
TT068 | 212 | 70.55 | 62.23 | − (5 dpo) | + | + | Recovered |
TT070 | 7 | 10.65 | 39.41 | − | − | + | Recovered |
TT075 | 12 | 7.96 | 36.37 | − | − | + | Recovered |
TT076 | 6 | 6.06 | 12.28 | − | − | + | Recovered |
TT078 | 6 | 12.80 | 53.41 | − | − | + | Recovered |
TT080 | 11 | 7.23 | 20.38 | − | ± | − | Acute |
TT087 | 150 | 50.79 | 103.31 | N/A | − | + | Recovered |
TT090 | 460 | 46.95 | 42.65 | N/A | − | + | Recovered |
TT092 | 360 | 28.44 | 49.20 | N/A | − | + | Recovered |
TT095a | 4 | 92.49 | 95.52 | − | − | − | Negative |
TT095b | 22 | 86.41 | 105.19 | − | − | − | Negative |
TT095c | 147 | 119.61 | 125.85 | − (4 dpo) | − | − | Negative |
TT095d | 399 | 112.67 | 104.57 | − (4 dpo) | − | − | Negative |
TT101 | 5 | 68.16 | 64.41 | − | − | − | Negative |
TT103 | 30 | 7.68 | 16.32 | − | − | + | Recovered |
TT107 | 30 | 8.11 | 20.72 | − | − | + | Recovered |
TT114 | 10 | 42.24 | 79.73 | − | − | + | Recovered |
TT120 | 11 | 96.75 | 101.83 | − | ± | + | Recovered |
TT122 | 23 | 35.17 | 30.08 | − | − | + | Recovered |