Table 2 Comparison of demographic features between fresh and paraffin-embedded papillary thyroid cancer biopsy samples
From: Traces of JC polyomavirus in papillary thyroid cancer: a comprehensive study in Iran
Fresh biopsy samples (n = 412) | Paraffin-embedded biopsy sample (n = 645) | P-value | |
|---|---|---|---|
Mean age ± SD | 42.7 ± 13.4 | 42.5 ± 12.9 | 0.065 |
Sex (male/female) | 117/295 (28.4/71.6%) | 158/487 (24.5/75.5%) | 0.172 |
Smoking (yes/no) | 113/299 (27.4/72.6%) | 389/256 (60.3/39.7%) | 0.472 |
Tumor size (mean ± SD, mm) | 2.1 ± 1.2 | 1.9 ± 0.9 | 0.065 |
Multifocality (Unifocal/Multifocal) | 248/164 (60.2/39.8%) | 420/225 (65.1/34.9%) | 0.117 |
Lymphovascular invasion (yes/no) | 102/310 (24.8/75.2%) | 92/553 (14.3/85.7%) | < 0.001* |
Extrathyroidal extension (yes/no) | 84/328 (20.4/79.6%) | 76/569 (11.8/88.2%) | < 0.001* |
Lymph node involvement (yes/no) | 174/238 (42.2/57.8%) | 231/414 (35.8/64.2%) | 0.038* |
Capsular invasion (yes/no) | 232/180 (56.3/43.7%) | 269/376 (41.7/58.3%) | < 0.001* |
JCV (positive/negative) | 72/340 (17.5/82.5%) | 42/603 (6.5/93.5%) | < 0.001* |
JCV DNA load (mean ± SD) | 1.8 × 10–1 ± 0.4 × 10–1 | 0.3 × 10–4 ± 0.1 × 10–4 | < 0.001* |