Table 1 Demographic features in Iranian Patients with papillary thyroid cancer according to JCV LT-Ag positivity
From: Traces of JC polyomavirus in papillary thyroid cancer: a comprehensive study in Iran
JCV LT-Ag positivity | Total | P-value | ||
|---|---|---|---|---|
Positive | Negative | |||
Patients (No) | 114 (10.8%) | 943 (89.2%) | 1057 (100.0%) | – |
Mean age ± SD | 40.7 ± 13.3 | 42.8 ± 13.1 | 42.5 ± 13.1 | 0.065 |
Sex (male/female) | 44/70 (38.6/61.4%) | 231/712 (24.5/75.5%) | 275/782 (26.0/74.0%) | 0.001* |
Smoking (yes/no) | 72/42 (63.2/36.8%) | 430/513 (45.6/54.4%) | 502/551 (47.5/52.5%) | 0.275 |
Tumor size (mean ± SD, mm) | 2.1 ± 1.3 | 1.9 ± 0.9 | 1.9 ± 1.0 | 0.448 |
Multifocality (unifocal/multifocal) | 47/67 (41.2/58.8%) | 621/322 (65.9/34.1%) | 668/389 (63.2/36.8%) | < 0.001* |
Lymphovascular invasion (yes/no) | 66/48 (57.9/42.1%) | 128/815 (13.6/86.4%) | 194/863 (18.4/81.6%) | < 0.001* |
Extrathyroidal extension (yes/no) | 67/47 (58.8/41.2%) | 93/850 (9.9/90.1%) | 160/897 (15.1/84.9%) | < 0.001* |
Lymph node involvement (yes/no) | 71/43 (62.3/37.7%) | 334/609 (35.4/64.6%) | 405/652 (38.3/61.7%) | < 0.001* |
Capsular invasion (yes/no) | 70/44 (61.4/38.6%) | 431/512 (45.7/54.3%) | 501/556 (47.4/52.6%) | 0.002* |