HPV genotype | Positive cases | Percentage for all sample (%) | 95% CI for all samples (%) | 2015 (n = 252) | 2016 (n = 1900) | 2017 (n = 2728) | 2018 (n = 5907) | 2019 (n = 13,079) | χ2 | P | gamma value |
---|---|---|---|---|---|---|---|---|---|---|---|
Any HPV | 4489 | 18.81 | (18.31–19.30) | 142 (56.35%) | 472 (24.84%) | 582 (21.33%) | 1009 (17.08%) | 2284 (17.46%) | 155.025 | < 0.001 | − 0.125 |
HR HPV | 2781 | 11.65 | (11.24–12.06) | 73 (28.97%) | 283 (14.89%) | 370 (13.56%) | 657 (11.12%) | 1398 (10.69%) | 74.789 | < 0.001 | − 0.115 |
HPV-16 | 559 | 2.34 | (2.15–2.53) | 17 (6.75%) | 62 (3.26%) | 87 (3.19%) | 139 (2.35%) | 254 (1.94%) | 37.216 | < 0.001 | − 0.185 |
HPV-18 | 239 | 1.00 | (0.87–1.12) | 6 (2.38%) | 33 (1.74%) | 23 (0.84%) | 65 (1.10%) | 112 (0.86%) | 11.689 | 0.001 | − 0.152 |
HPV-26 | 13 | 0.05 | (0.02–0.08) | 0 (0.0%) | 3 (0.16%) | 1 (0.04%) | 3 (0.05%) | 6 (0.05%) | 1.308 | 0.253 | − 0.200 |
HPV-31 | 82 | 0.34 | (0.26–0.41) | 3 (1.19%) | 7 (0.37%) | 7 (0.26%) | 15 (0.25%) | 50 (0.38%) | 0.992 | < 0.001 | 0.066 |
HPV-33 | 149 | 0.62 | (0.52–0.72) | 12 (4.76%) | 20 (1.05%) | 19 (0.70%) | 42 (0.71%) | 56 (0.43%) | 37.537 | < 0.001 | − 0.313 |
HPV-35 | 119 | 0.50 | (0.40–0.58) | 9 (3.57%) | 13 (0.68%) | 22 (0.81%) | 26 (0.44%) | 49 (0.37%) | 25.027 | < 0.001 | − 0.281 |
HPV-39 | 324 | 1.36 | (1.21–1.50) | 10 (3.97%) | 44 (2.32%) | 48 (1.76%) | 69 (1.17) | 153 (1.17%) | 25.858 | < 0.001 | − 0.180 |
HPV-45 | 80 | 0.34 | (0.26–0.40) | 2 (0.79%) | 10 (0.53%) | 14 (0.51%) | 13 (0.22%) | 41 (0.31%) | 4.187 | 0.041 | − 0.131 |
HPV-51 | 273 | 1.14 | (1.00–1.27) | 14 (5.56%) | 35 (1.84%) | 37 (1.36%) | 58 (0.98%) | 129 (0.99%) | 27.131 | < 0.001 | − 0.185 |
HPV-52 | 705 | 2.95 | (2.73–3.16) | 30 (11.90%) | 69 (3.63%) | 91 (3.34%) | 151 (2.56%) | 364 (2.78%) | 22.886 | < 0.001 | − 0.099 |
HPV-53 | 399 | 1.67 | (1.50–1.83) | 11 (4.37%) | 42 (2.21%) | 54 (1.98%) | 95 (1.61%) | 197 (1.51%) | 12.594 | < 0.001 | − 0.120 |
HPV-56 | 308 | 1.29 | (1.14–1.43) | 10 (3.97%) | 31 (1.63%) | 33 (1.21%) | 73 (1.24%) | 161 (1.23%) | 4.866 | 0.027 | − 0.069 |
HPV-58 | 495 | 2.07 | (1.89–2.25) | 22 (8.73%) | 52 (2.74%) | 65 (2.38%) | 116 (1.96%) | 240 (1.84%) | 26.920 | < 0.001 | − 0.145 |
HPV-59 | 257 | 1.08 | (0.94–1.20) | 7 (2.78%) | 42 (2.21%) | 35 (1.28%) | 46 (0.78%) | 127 (0.97%) | 21.993 | < 0.001 | − 0.167 |
HPV-66 | 209 | 0.88 | (0.75–0.99) | 11 (4.37%) | 17 (0.89%) | 27 (0.99%) | 47 (0.80%) | 107 (0.82%) | 6.964 | 0.009 | − 0.098 |
HPV-68 | 132 | 0.55 | (0.45–0.64) | 1 (0.40%) | 6 (0.32%) | 10 (0.37%) | 32 (0.54%) | 83 (0.63%) | 5.044 | 0.025 | 0.171 |
HPV-82 | 92 | 0.39 | (0.30-.46) | 6 (2.38%) | 16 (0.84%) | 7 (0.26%) | 18 (0.30%) | 45 (0.34%) | 12.653 | < 0.001 | − 0.184 |
HR + LR | 707 | 2.96 | (2.74–3.17) | 42 (16.67%) | 87 (4.58%) | 85 (3.12%) | 154 (2.61%) | 339 (2.59%) | 67.915 | < 0.001 | − 0.176 |
LR HPV | 1001 | 4.19 | (3.94–4.44) | 27 (10.71%) | 102 (5.37%) | 127 (4.66%) | 198 (3.35%) | 547 (4.18%) | 11.973 | 0.001 | − 0.048 |
HPV-6 | 309 | 1.29 | (1.15–1.43) | 29 (11.51%) | 44 (2.32%) | 51 (1.87%) | 52 (0.88%) | 133 (1.02%) | 91.034 | < 0.001 | − 0.294 |
HPV-11 | 194 | 0.81 | (0.69–0.92) | 18 (7.14%) | 30 (1.58%) | 25 (0.92%) | 38 (0.64%) | 83 (0.63%) | 54.330 | < 0.001 | − 0.286 |
HPV-40 | 39 | 0.16 | (0.11–0.21) | 3 (1.19%) | 6 (0.32%) | 6 (0.22%) | 10 (0.17%) | 14 (0.11%) | 12.752 | < 0.001 | − 0.351 |
HPV-42 | 84 | 0.35 | (0.27–0.42) | 0 (0.00%) | 12 (0.63%) | 9 (0.33%) | 14 (0.24%) | 49 (0.37%) | 0.227 | 0.634 | 0.004 |
HPV-43 | 265 | 1.11 | (0.97–1.24) | 8 (3.17%) | 27 (1.42%) | 37 (1.36%) | 68 (1.15%) | 125 ().96%) | 11.083 | 0.001 | − 0.147 |
HPV-44 | 205 | 0.86 | (0.74–0.97) | 4 | 15 | 22 | 46 | 118 | 0.086 | 0.769 | 0.037 |
 |  |  |  | (1.59%) | (0.79%) | (0.81%) | (0.78%) | (0.90%) |  |  |  |
HPV-55 | 209 | 0.88 | (0.75–0.99) | 12 (4.76%) | 20 (1.05%) | 38 (1.39%) | 31 (0.52%) | 108 (0.83%) | 15.286 | < 0.001 | − 0.137 |
HPV-61 | 362 | 1.52 | (1.36–1.67) | 8 (3.17%) | 30 (1.58%) | 36 (1.32%) | 75 (1.27%) | 213 (1.63%) | 0.072 | 0.789 | 0.047 |
HPV-81 | 285 | 1.19 | (1.05–1.33) | 8 (3.17%) | 22 (1.16%) | 37 (1.36) | 71 (1.20%) | 147 (1.12%) | 2.584 | 0.108 | − 0.066 |
HPV-83 | 48 | 0.20 | (0.14–0.25) | 1 (0.4%) | 6 (0.32%) | 6 (0.22%) | 9 (0.15%) | 26 (0.20%) | 0.909 | 0.340 | − 0.065 |