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Table 2 Comparison of RT-RAA-Cas12a-based fluorescence and lateral flow strip (LFS) and RT-PCR of norovirus genotype GII.4 and GII.17 in 80 clinical samples

From: Ultrasensitive and visual detection of human norovirus genotype GII.4 or GII.17 using CRISPR-Cas12a assay

Assay

Number of samples

Detection coincidence rate with RT-PCR for 70 positive samples (%)

Detection coincidence rate with RT-PCR for 10 negative samples (%)

Positive

Negative

RT-RPA-Cas12a-based fluorescence

67

10

95.7

100

RT- RPA-Cas12a-based-LFS

66

10

94.3

RT-PCR

70

10