Fig. 2From: HIV-1 bispecific antibody iMab-N6 exhibits enhanced breadth but not potency over its parental antibodies iMab and N6Binding characterisation of purified antibodies by ELISA. A Left panel: HIV-1 Env targeting moieties (N6 and iMab-N6) were tested against gp140FVCGCN4 with iMab being used as a negative control. A Right panel: iMab-N6 was used at double the concentration of N6 to try and correct for the difference in binding affinity seen in A Left panel. B CD4 binding moieties (iMab and iMab-N6) were tested against 4dCD4 with N6 serving as an appropriate negative controlBack to article page