Fig. 5

A Immunohistochemical results: CK7 foci (+), CK18 (weak + - +), CK19 (weak + - +), CK20 (−), CDX₂ (weak + - +), AFP (−), Hepar1 (−), Arg-1 (−), GATA-3 (−), Vim (−), P40 a little (+), CD117 (−), CerbB2 (−), Ki-67 (+) 80–90%, EBV in situ hybridization: tumor cells EBER (+). Combining liver puncture with morphology, immunohistochemistry, and EBV in situ hybridization results, it was consistent with EB virus-associated poorly differentiated carcinoma (magnification, × 100). B Consider EBV infection-associated poorly differentiated cholangiocarcinoma (LELC morphology) magnification, × 200)