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Fig. 7 | Virology Journal

Fig. 7

From: Preparation of the luciferase-labeled antibody for improving the detection sensitivity of viral antigen

Fig. 7

Clinical Sensitivity and specificity comparison of the Nluc-AMCA with commercial ELISA and colloid gold strip kit. A: Scatter diagram of Nluc-AMCA; B: ROC curve of the Nluc-AMCA, commercial ELISA and colloid gold strip. SARS-CoV-2 negative NPS (n = 48) were applied to Nluc-AMCA to assess specificity and 32 positive NPS were used to test sensitivity. All of the samples were identified by qPCR. The clinical sensitivity and specificity of the Nluc-AMCA were reached 75% and 100% respectively. AUC for the Nluc-AMCA, commercial ELISA and colloid gold strip is 0.9014, 0.8750, 0.8516, respectively

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