Table 2 List of up- and down-miRNAs and their corresponding putative targets

hsa-miR-7704

GNG7, GNG3, CTD-2207O23.12, FLJ27365, SUSD2, TULP3, HSPB6, NDUFS8, TUBB4A, PPP1R27, DNAH17, CLIP3, LEF1, C8G, GDE1, FIBCD1, RTBDN, RUVBL2, GNAO1, DERL3, MT-ND4L, NINJ1, VAX1, ANKRD53

hsa-miR-4485-3p

CHMP4C, PARK7, LACTB2

hsa-miR-7977

MUC19, TRAPPC2P1, AC106017.1, PEX26, PRR13, SMIM12, KDELR1, ORAI2, C18orf32, UBC, TRAPPC2, ZNF70, C1orf210, SMUG1, TNFRSF13C, MSRB1, CD3D, APOBEC3F, PHB2, RPL24, PCBP1, SSH2, CD84, TRUB2, PRR5L, CDNF, RPL37A, RP11-47I22.3, ZNF726, NDUFA7, MRPL27, UQCR11, MRPS12, COX6B1, MAVS, TBC1D16, PCNP, C14orf2, LPAR2, CLEC17A, MTHFD1, IBA57

hsa-miR-99a-5p

EPDR1, AGO2, TTC39A, ST6GALNAC4, AP1AR

hsa-miR-218-5p

GLCE, SERP1, MOSPD1, C3orf70, TUB, VOPP1, NAPEPLD, TPD52, KCTD16, SGCZ, EIF5A2, HPGD, SAMD12, ONECUT2

hsa-miR-4516

SPATA33, WNT8B, ZBTB20, ASXL2, AL441883.1, RP11-210M15.2, SCN3B, PPP1R11, RP11-664D7.4, FBXO48, KLF8, GRIK5, GRIN2B, KSR2, PIGO, ING4, RAB19, CBL, PIP, RHO, FBXL20, RBM23, ZNF133, CCDC23, IGF2R

hsa-miR-4508

BOK, CLYBL, AKT2, ARHGAP39, PPDPF, TBX1, REPIN1, LSM7, VTN, SYT7, TMEM141, COL20A1, NFIX, VWA1, WNK2, SH3GL1, SURF4, NAPA, SLC7A5, PRX, CRHR2, ATG4B

hsa-miR-9901

THRSP

hsa-miR-409-3p

FAM229B

hsa-miR-3195

REPIN1, ZNF74, MZF1, NRG2, C8orf82, PAOX, APC2, AL591479.1, C19orf26, IFLTD1, AC103801.2, BRF1, LRRC14, C1orf229, EVX1, MT-ND4L, KIFC2, TUBB6, AL360004.1, KLHL3

hsa-miR-375-3p

RLF, POC1B, ELAVL4, COLCA2

Novel_29

–

Novel_68

–

Novel_12

–

Novel_81

Mir151b, LINC00273, RBPMS-AS1, GYG2P1, CNR2, 8-Sep, c7orf25, MIR4781, CECR2

Novel_105

SKOR2, B3GALT2, KIAA0513, MPDZ, RP1, COL19A1, SLC12A2

hsa-miR-9-5p

RTL1

hsa-miR-873-5p

MECP2, alas2, MAN2C1, c16orf62

hsa-miR-708-5p

SND1-IT1, GYG2P1, ZKSCAN8, KPNA4, FCAMR, C1orf74, POM121L2, MYO1E, GRIA4, G3BP1, TEX261, CARD14, CXCL9, SLC31A1, DRAM1, MAS1, GTF3C4, DCAF10, MDGA1, ASPA, TP53BP1, NNAT, MIR6132

hsa-miR-708-3p

DMRTC2

hsa-miR-663a

DND1, HOXA10-AS, colgalt2, RAB3B, ISLR2, KLHL21, TRIM36, TRPM2, DCTD, IDUA, TGFB1, USP14, KLHL42, OPRK1

hsa-miR-654-3p

BEAN1, AREL1

hsa-miR-619-5p

akap6, CEP250, MGA, UNC13C, MYO5A, ARFGEF3, DENND4C, FN1, AIM1, SMG1, NBEAL1, PLCE1, KALRN, URB1, DOCK9, ATM, TRPM7, TEP1, MYO10, ZNFX1

hsa-miR-4787-5p

LOC101928053, ZNF628, BCL9L, TMEM210, TMEM121, WT1, FMNL1, EP400, FZD4, UTF1, INHBB, PRMT2, ADCY8, ZNF414, AFDN, SOX9, FOXN1, MIR7855, RNF10, AP2B1

hsa-miR-4488

SEMA6C, ADAMTS8, RASD2, MADCAM1

hsa-miR-3960

SGK223, Tgfbr3l, RBM15B, TMEM158, USP51, c9orf69, LOC101928733, HPN-AS1, NEURL1B, ZNF337-AS1, NHSL2, FOXO6, LOC100128531, CNGA1, NANOS1, TUBB4B, USP7, RSBN1L, NOTUM, MANEAL, FMNL1, CNTN2, TBX1, GJD3, NKX2-5, MEX3D, GPR139, IRX5, KCMF1, SSNA1, EIF1, CEBPB, PLEKHG5, KCNG3, LONRF2, CHD3, CTNND2, GSG1L, LETM1, cenpv, C1QL3, ZNF219, OTUD1, ZNF367, UNCX, NKX6-1, RPRD2, CYGB, GUCY1A2, SETBP1, VEGFC, PCDH15, fam135b, 4-Mar, GATAD2B, ATP1B1, ZCCHC2, pelp1, BNIP2, PDX1, FOXF2, DNAJC1, ITM2B, CKAP4, BICDL1, BTF3L4, TRMT5, FAM193A, MTHFD1L, BCL11A, ARID1A, PLPPR5, PAPD7, PRDM13, PPP1R9B, BLMH, CCNY, TNKS2, EVX1, HOXA13, NOVA2, UBR5, BMF, MIB1, KIF3B, ADNP, RIMS4, SMARCB1, HCN2, RCOR1, SEPHS1, PGR, APBB1IP, DGKD, FAM50A, ARID1B, ADRB1, CLEC16A, CDK11A, CACNA2D2

hsa-miR-382-5p

LINC00301, TPST1, USP39, MED22

hsa-miR-381-3p

EHF, DUSP3

hsa-miR-370-3p

LOC101928535, PACS1, ZBTB39, ZC3H18, IL2RB, LAG3, PPP1R12A

hsa-miR-3648

GPC4

hsa-miR-3196

GLTSCR1

hsa-miR-199b-3p

PTPRF, c10orf2

hsa-miR-199a-5p

KCTD16, GOLGB1, CD5L

hsa-miR-199a-3p

PTPRF, c10orf2

hsa-miR-146a-5p

LOC101929662, ARID1A

hsa-miR-145-5p

SOCS7, LOC283887, RYR1, WWOX, wdr97, BEND3, COL4A3, RNF187, GRIP1, MYH15, SLC24A4, ARHGAP32, c10orf76, IPCEF1, cyp46a1

hsa-miR-143-3p

SPINT3

hsa-miR-137-3p

WBP1L, DR1, SSR3

hsa-miR-127-3p

MIR151A

hsa-miR-1273 h-5p

MIR4534, GRIN2B, ASB16-AS1, LOC100506321, PSMA2, LINC00847, LOC101927257, HOXB-AS1, FLJ43879, LOC729867, ZNF469, MIR28, RNPS1, TGM2, TLK1, ZKSCAN8, SVIP, GDAP2, RNF216P1, ZNF284, MRPL30, ZNF445, EWSR1, RNASE10, MXRA7, IL17RA, UMODL1, spryd4, SLC35E3, TRAPPC12, RNF150, SYAP1, SIN3A, ZNF558, cox11, METTL2B, LRPAP1, PPM1L, atad3b, TAB3, INO80C, PTGES, NXPE3, FHDC1, HRH4, RSPH3, ADGRE2, RREB1, TROVE2, MIR4781, PLEKHA3, GGCX, UMPS, NANOG, ZPR1, CLIP2, STK24, RNF125, MANBAL, EFS, PUS7, RBMS2, SCARB1, MED17, PHLPP2, CDH1, CASP10

hsa-miR-124-3p

CDK11B

hsa-miR-10b-5p

GABRB1

hsa-miR-10400-5p

DGKK, CTD-2194D22.4, CBR3-AS1, NUTM2B-AS1, FOXI3, SP5, MDM4, TSC22D2, ZBTB44, GRM7, NANOS1, ESPN, IRS2, ATP6V0A2, JAG2, BTBD6, EXT1, skida1, GAS1, GATA2, PDE4DIP, OLIG3, GRIN1, FOXG1, hsf5, ZDHHC14, OTP, XKR6, DNAJC21, CASKIN1, PRRX2, LARGE2, ZNF367, UNCX, DCLK3, PAXBP1, SPPL3, UBN2, SYN2, SCAF4, TRIP12, CABLES2, YTHDF1, ASTN2, SEMA6C, barhl2, LMO4, PCSK6, ZIC5, PHLDA1, FAM117B, GRHL1, PRR7, ZC3H4, COPB1, MGAT3, KLF2, MMP24, ETF1, IRF2BPL, EXOC8, cpeb3, UBE2R2, RIC1, CCNE1, NOVA2, CA2, CD99L2, HCN2, hivep1, KAT6A, PHLPP1, KCNN2, ATP2A3, SLK, slc9a3r2, POLD1, QSER1, CAMK2B

hsa-miR-10396b-3p

c3orf70, AMER3, SOX12, USP38, ZNF219, LILRB2, PLBD1, CSK

hsa-let-7c-5p

SPACA6P-AS, PFKFB1, DICER1

hsa-miR-4286

PARVG, CBX2, RP11-210M15.2, WLS, CD59, FAM222B, DYNLL2, PHF1, APLN, H1F0, EMC2, PRX, PPIL1, B4GALT7, ECHDC1, TNFAIP8L3, C14orf144, C3orf62, TEX22, CTRC, ZBTB7B, FOXO4, TMSB4X, CDK9

hsa-miR-1275

PPP2R2D, KCNC3, SPRED3, NFIC, MECP2, NOVA2, CTB-54O9.9, ZBTB7A, PRKACA, VAMP2, SPA17, LUC7L, IGF2, KIR3DX1, NFIX, ID1, SCRT2, GATSL2, SDHAF1, SIRT2, APLN, HMGA1, PIN1, CEBPG, CBLN1, FOXP4, NEUROD2, SPOCK1, DIRAS2, GPBP1, PRR26, RAB11FIP5, LRRC28, SH3PXD2A, TCEB2, SLC8A2, UBTF, MSI1, ZSWIM4, HSPB6, URM1, NUDT18, HRK, EMC10, SPTAN1, DDA1, DAGLA, ACTB, FAM155B, PCDHGA12, TSPAN14, NTPCR, GRWD1, PCDHGA10, CD8B, LURAP1, RALY, MTHFR, PKNOX2, AL117190.3, CLIP3, MDK, STX8, MXD1, BZRAP1, WNT7B, IGF1, HPCA, C1orf106, PIP4K2B, CISD3, DUSP8, DOT1L, CYP2C19, ABI2, ZBED3, SPINT1, SPRR1B, ATXN1L, BCL7A, SYT7, FTO, CTSB, PIANP, KIAA0141, RP11-195F19.5, C17orf96, NKD1, C11orf42, TEKT4, MAPK4, M6PR, TBC1D7, CXADR, HSD11B2, SLC22A25, RBM23, OVOL2, UBALD1, THSD4, PURG, PTGIS, FN3K, RNASE13, MDGA1, MPZ, NDEL1, VPS37D, DDX17, TBC1D16, GATAD2B, ENY2, REEP6, KLK4, PDE4A, ZNF385B, NAPA, ZNF677, SORBS3, SLC25A42, GINS2, CNIH2, SLC25A23, RAB3A, FAM216B, CBX5, ZNF691, DOK1, RP11-368I7.4, PAX5, AGFG2, POU2F2, CD3E, CUX1, HOXC12, SLC7A8, CRYBB1, SCUBE3, FGF1, RARA, S100G, AC007405.2, C12orf75, NR1H4, RNF115, GJB4, CLDN2, FAM50B, HNRNPAB, IGF2BP1, DUSP2

Novel_132

ZNF773

Novel_114

SIVA1, CREBBP

hsa-miR-940

PNMA3, UBE2Q1

hsa-miR-550a-5p

LOC102724908, MIR550A3, MIR550A1, MIR550A2, EPM2AIP1, PCDH15, FEM1A, DHCR24, SLC44A1, SLC11A1

hsa-miR-4758-3p

LOC105370648, LOC101929054, JRK, SPANXA2, DCAF12L1, SPANXA1, SPANXD, PTCH1, HMCES, AEN, UACA, SH2B3

hsa-miR-455-3p

PIK3R1

hsa-miR-324-5p

CTNND2, TIMP1

hsa-miR-324-3p

PWRN1, FAM118B, HSF1, MAF1, ZNF556, PRNP, CLSTN1, ZNF672, TRUB2, TMEM41A, ZBTB7B, ANKRD9, HERC5, RNF121, RNF112, spdef, ZNF644, EPX, qsox1, POLD2, MYH14, HERC1, CAPN15, coro1a, DSP, CYP26A1, QSER1, SYNE2

hsa-miR-30b-3p

LOC101927460, ITSN1, FAM210A, lcmt2, ANAPC16, ADCY1, SVOPL, UBR2

hsa-miR-23a-5p

RINL, MYO1D, KSR2, ZNF577, CHRNA2, HGD, TNFSF8, TXK, CTSA

hsa-miR-210-5p

LINC00639, PRSS53

hsa-miR-210-3p

SLC25A28, ADAMTS8

hsa-miR-193b-5p

SEPHS2, OR8J3

hsa-miR-138-5p

RNF103, MUC5AC, gaa, SHISA5, PLA2G4D, CCDC3, DLX4, IPCEF1, ITIH4

hsa-miR-130b-3p

HTT, TCF4, fam47e, EIF5B, IL12RB1, EXOSC7

hsa-miR-130a-3p

TCF4, DDX17

hsa-miR-1260b

MAML2, WDR26, PHF19

hsa-miR-1260a

ngb

hsa-let-7e-3p

SPACA6P-AS

hsa-let-7b-3p

Mirlet7a1, MIRLET7A2, MIR4763, KIAA0825, AIM1