Association between common vaginal and HPV infections and results of cytology test in the Zhoupu District, Shanghai City, China, from 2014 to 2019

Table 3 Characteristics of 23,724 women with and without vaginal infection

	Vaginal infection-positive (n = 1265)	Vaginal infection-negative (n = 22,459)	P value	OR (95% CIs)
Age (years old)
Mean (SD)	34.4(9.5)	36.9(11.5)
Median (Min, Max)	32(16–67)	34(15–94)
< = 30	543(42.9%)	8220(36.6%)	0.0088	0.2(0.2–0.3)
30–40	354(28.0%)	6317(28.1%)	0.5283	0.2(0.2–0.2)
> = 40	368(29.1%)	7922(35.3%)	0.0000	0.2(0.1–0.2)
HPV infections
Positive	243(19.2%)	3573(15.9%)	0.0021	1.3(1.1–1.5)
Negative	1022(80.8%)	18,886(84.1%)
TCT
Normal	1222(96.6%)	18,000(80.1%)	0.0000	7.0(5.2–9.6)
Abnormal	43(3.4%)	4459(19.9%)
Pathology
CIN	7(0.6%)	277(1.2%)	0.0259
Cervical cancer	0	1(0%)
Highly-suspected precancerous lesions	36(2.8%)	4181(18.6%)

0.0000: 29.1% of women with vaginal infection were older than 40 years, while 35.3% of women without vaginal infection were older than 40 years (P < 0.001), 0.0021: The HPV infection rate in the vaginal infection-positive group (80.8%) was higher than that in the vaginal infection-negative group (15.9%) (P < 0.001), 0.0000: The difference was also noted between the vaginal infection-positive group and the vaginal infection-negative group (P < 0.001)
OR (95% CIs), Odd Ratio (95% Confidence Intervals)

ISSN: 1743-422X