Association between common vaginal and HPV infections and results of cytology test in the Zhoupu District, Shanghai City, China, from 2014 to 2019

Table 2 Characteristics of 23,724 women with and without HPV infection

	HPV-positive (n = 3816)	HPV-negative (n = 19,908)	P value	OR (95% CIs)
Age (years old)
Mean (SD)	36.7(11.34)	37.08(12.03)
Median (Min, Max)	34.0(15–87)	36.7(16–94)
< = 30	1446(37.9%)	7317(36.8%)	0.0001	1.0(1.0–1.1)
30–40	952(24.9%)	5719(28.7%)	0.529	0.8(0.8–0.9)
> = 40	1418(37.2%)	6872(34.5%)	0.046	1.1(1.0–1.2)
Vaginal infections
Positive	243(6.4%)	1022(5.1%)	0.0021	1.26(1.1–1.5)
Negative	3573(93.6%)	18,886(94.9%)
TCT
Normal	2609(68.4%)	16,613(83.4%)	0.0000	0.43(0.4–0.5)
Abnormal	1207(31.6%)	3295(16.6%)
Pathology
CIN	235(6.2%)	49(0.2%)	0
Cervical cancer	0	1(0%)
Highly-suspected precancerous lesions	972(25.5%)	3245(16.3%)

0.0001: Among women who were younger than 30 years old, 37.9% were HPV-positive and 36.8% were HPV-negative (P < 0.001), 0.0021: The HPV-positive group had a slightly higher vaginal infection rate (6.4%>5.1%) than the HPV-negative group (P < 0.01), 0.0000: there was a significant difference in abnormal TCT results between the HPV-positive group and the HPV-negative group (P< 0.001)
OR (95% CIs) Odd Ratio (95% Confidence Intervals)

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