Fig. 8
Efficacy of DNA vaccine and combination therapy in tumor cell (TC-1)-bearing mice. Tumor tissue was established through injection of TC-1 cells (1 × 10.5) subcutaneously. After twice immunization, tumor volume was calculated until 6th week post tumor challenge. The comparison of the difference between E7&IL-24 group and other groups (DNA E7, IL-24, pcDNA and PBS groups) was significant (p < 0.001). Data are represented as the mean ± SD (n = 6 mice per group). Significance for mouse survival was determined by Student’s t-test