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Fig. 6 | Virology Journal

Fig. 6

From: Enhanced synergistic antitumor effect of a DNA vaccine with anticancer cytokine, MDA-7/IL-24, and immune checkpoint blockade

Fig. 6

The levels of caspase-9 and TRAIL proteins in the tumor microenvironment. Mice were challenged with TC-1 tumor cells and immunized as described in the text. One week after immunization, mice groups were sacrificed and tumor tissue extracted and homogenized to form a uniform tumor lysate. The concentration of caspase-9 (A) and TRAIL (B) in tumor lysates determined by ELISA. Results are representative mean ± SD of three independent experiments. *P < 0.05; ***P < 0.001

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