Fig. 2
From: Duck hepatitis A virus type 1 mediates cell cycle arrest in the S phase
Viral activity is the cause of cell cycle arrest in the S phase. A At 24 h or 48hpi, DEFs infected with mock or UV-inactivated DHAV-1 at MOI of 1 were collected to analyze cell-cycle profiles by flow cytometry. B The histograms were analyzed by the ModFit LT program to display the cell cycle distribution. C DEFs were infected with DHAV-1 and UV-DHAV-1 at MOI of 1, respectively. The X-axis shows the different time points, and the Y-axis represents the logarithm of the number of viral RNA copies. D The expression of VP3 protein in DEFs at 24 h or 48hpi. Differences between the 2 groups were analyzed using Student's t-test and considered significant at ****P < 0.0001