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Table 4 Classification results for HCC/CHB patients of different HBV genotypes using SLR

From: Sparse logistic regression revealed the associations between HBV PreS quasispecies and hepatocellular carcinoma

 

Genotype B (λ = 0.58)

Genotype C

Genotype C (λ = 0.53)

Genotype B

Training set

Test set*

Test set#

Training set

Test set*

Test set#

Accuracy

0.924(0.028)

0.778

0.741

0.870 (0.023)

0.776

0.741

Sensitivity

0.678(0.122)

0.583

0.915

0.840 (0.064)

0.864

0.500

Specificity

0.999(0.006)

0.933

0.346

0.890 (0.036)

0.577

0.933

AUC

0.861(0.061)

0.706

0.754

0.843 (0.027)

0.767

0.722

  1. *Test results were produced using SLR model trained by patients with the same genotype of HBV
  2. #Test results were produced using SLR model trained by patients with the other genotype of HBV
  3. AUC Area under the receiver operating characteristic curve; CHB Chronic hepatitis B; HCC Hepatocellular carcinoma; SLR Sparse logistic regression
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Virology Journal

ISSN: 1743-422X