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Table 2 Prevalence of herpesvirus reactivation, viral load, and correlation of herpesvirus reactivation with the SARS-CoV-2 load

From: Herpesvirus and neurological manifestations in patients with severe coronavirus disease

Virus Prevalence n (%) SARS-CoV-2 load (mean ± DP) Kendall’s Tau-b Correlation coefficient (coefficient; p value)
HSV-1 9/53 (17) 3.54E+9 ± 1.0E+10 0.556; p = 0.037*
HSV-2 1/53 (1.9) 1930
EBV 15/53 (28.3) 1.52E+12 ± 3.99E+12 − 0.162; p = 0.400
CMV 23/53 (43.4) 1.31E+11 ± 3.28E+11 0.020; p = 0.895
VZV 4/53 (7.5) 1.32E+10 ± 2.26E+10
HHV-6 25/53 (47.2) 8.52E+11 ± 2.14E+12 − 0.223; p = 0.102
HHV-7 21/53 (39.6) 2.83E+11 ± 6.57E+11 0.181; p = 0.251
HHV-8 9/53 (17) 9.50E+5 ± 2.40E+6 0,355; p = 0.139
  1. aKendall’s Tau-b coefficient indicates the association of the SARS-CoV-2 load with the load viral of each herpesvirus. Missing values indicate that the test could not be conducted owing to a small sample size
  2. SARS-CoV-2 severe acute respiratory syndrome coronavirus 2, HSV herpes simplex virus, VZV varicella zoster virus, EBV Epstein–Barr virus, CMV cytomegalovirus, HHV human herpesvirus
  3. *Statistical significance