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Table 2 Prevalence of herpesvirus reactivation, viral load, and correlation of herpesvirus reactivation with the SARS-CoV-2 load

From: Herpesvirus and neurological manifestations in patients with severe coronavirus disease

Virus

Prevalence n (%)

SARS-CoV-2 load (mean ± DP)

Kendall’s Tau-b Correlation coefficient (coefficient; p value)

HSV-1

9/53 (17)

3.54E+9 ± 1.0E+10

0.556; p = 0.037*

HSV-2

1/53 (1.9)

1930

–

EBV

15/53 (28.3)

1.52E+12 ± 3.99E+12

− 0.162; p = 0.400

CMV

23/53 (43.4)

1.31E+11 ± 3.28E+11

0.020; p = 0.895

VZV

4/53 (7.5)

1.32E+10 ± 2.26E+10

–

HHV-6

25/53 (47.2)

8.52E+11 ± 2.14E+12

− 0.223; p = 0.102

HHV-7

21/53 (39.6)

2.83E+11 ± 6.57E+11

0.181; p = 0.251

HHV-8

9/53 (17)

9.50E+5 ± 2.40E+6

0,355; p = 0.139

  1. aKendall’s Tau-b coefficient indicates the association of the SARS-CoV-2 load with the load viral of each herpesvirus. Missing values indicate that the test could not be conducted owing to a small sample size
  2. SARS-CoV-2 severe acute respiratory syndrome coronavirus 2, HSV herpes simplex virus, VZV varicella zoster virus, EBV Epstein–Barr virus, CMV cytomegalovirus, HHV human herpesvirus
  3. *Statistical significance
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Virology Journal

ISSN: 1743-422X