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Fig. 3 | Virology Journal

Fig. 3

From: Anti-L1 antibody-bound HPV16 pseudovirus is degraded intracellularly via TRIM21/proteasomal pathway

Fig. 3

Determination for HPV16 PsV load of the infected cells by qPCR assay. A represents the specificity and sensitivity of qPCR assay; B represents an optimal amount of anti-L1 antibody to bind to HPV16 PsV; C represents the expression level of TRIM21 trigged by HPV16 PsV-bound anti-L1 antibody; D represents the anti-L1 antibody-mediated degradation of HPV16 PsV; E represents the impact on the degradation of anti-L1-bound HPV16 PsV by inhibiting VCP and proteasome activity. All experiments were performed in triplicate, and data are expressed as mean ± SD (n = 3). Error bars represent the SD of replicating data points. *P < 0.05; **< 0.01; ***< 0.001, compared to the control

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