Fig. 2
From: Effective protection of ZF2001 against the SARS-CoV-2 Delta variant in lethal K18-hACE2 mice
Survival curves, lung histopathology, virus gene copy numbers in lungs, and Nab titers of Al + WT, RDINA + WT, ZF2001 + WT, Al + Delta, RDINA + Delta, and ZF2001 + Delta groups. a Survival curves. b Lung histopathology (inflammatory cell infiltration indicated by black arrows, lung interstitial thickness indicated by yellow arrows, hyperemia indicated by blue arrows, hemorrhages indicated by red arrows, and epithelial cell necrosis and shed indicated by green arrows). c Histopathological score. d, e SARS-CoV-2N and ORF 1ab gene copy numbers. f, g Nab titers for WT and Delta variant. Antibody titers were transformed into log2 values to calculate geometric means and 95% confidence intervals. d.p.i, days post infection. ↓, decrease. ↑, increase. lg, log10. * = P < 0.05, ** = P < 0.01. ns, non-significance