Fig. 5

Overview of the non-coding tandem repeat region present between E4.1 CDS and RH5 CDS. An alignment is shown of the non-coding region between positions 25,389 and 27,017 bp of the BadV-7 S427/18 strain genome in comparison to the equivalent region of the Ovine Adenovirus 7 (OAdV-7) genome. The arrows represent the E4.1 and RH5 open reading frames of of BAdV-7 (pink) and OAdV-7 (blue). The boxes represent the tandem sequence repeats of varying length. Each color represents a unique sequence. The older Fukuroi strain and the TS-GT vaccine strain (based on Fukuroi) are identical in this region and share the same repeat sequences. The newer strains are variable to each other and to the original Japanese strains. The newly identified German strain S427/18 has an insertion of 17 bp in comparison to the three published BAdV-7 strains and a deletion of 76 bp