Skip to main content

Table 2 Association between WHO score and MIRNA sequences. The results are reported as crude and sex- and age-adjusted incidence rate ratio (IRR) values and corresponding 95% confidence intervals (95% CIs)

From: Plasma Torquetenovirus (TTV) microRNAs and severity of COVID-19

 

WHO score ≥ 5

(N = 27)

WHO score < 5

(N = 29)

IRRa

(95% CI)

Adjusted IRR

(95% CI)

TTV DNA, copies/ml

    

 Negative (= 10), N (%)

12 (44)

11 (38)

Ref.

Ref.

 Positive (> 10), N (%)

15 (56)

18 (62)

0.87 (0.51–1.50)

0.84 (0.47–1.51)

miRNA t1a, copies/ug RNA

    

 Negative (= 10), N (%)

20 (74)

19 (66)

Ref.

Ref.

 Positive (> 10), N (%)

7 (26)

10 (34)

0.80 (0.42–1.53)

0.77 (0.41–1.44)

miRNA t3b, copies/ug RNA

    

 Negative (= 10), N (%)

7 (26)

13 (45)

Ref.

Ref.

 Positive (> 10), N (%)

20 (74)

16 (55)

1.58 (0.82–3.09)

1.46 (0.74–2.88)

miRNA tth8, copies/ug RNAb

    

 ≤ 3080, N (%)

10 (37)

20 (69)

Ref.

Ref.

 > 3080, N (%)

17 (63)

9 (31)

1.96 (1.10–3.50)

2.04 (1.14–3.63)

  1. aIncidence rate ratio (IRR) was calculated using Poisson regression models with robust variance
  2. bAs the TTV miRNA tth8 exhibited a low number of negative values, the median values (3080 copies/μg RNA) obtained using all positive data was used for dichotomous variables. Thus, for miRNA tth8, the data reported in the WHO score ≥ 5 and WHO score < 5 were the number of samples with values ≤ 3080 and those > 3080
Back to article page

Virology Journal

ISSN: 1743-422X