Skip to main content
Fig. 5 | Virology Journal

Fig. 5

From: All-trans retinoic acid increases the pathogenicity of the H9N2 influenza virus in mice

Fig. 5

Effects of therapeutic dose of ATRA on lung gross pathology of mice infected with H9N2 virus. ah are the lungs of mice at 19 days after inoculation. a Blank group, mice receiving sterile PBS inoculation and cottonseed oil injection at 0–9 days after inoculation; bd ATRA1-ATRA3 group, mice receiving sterile PBS inoculation and ATRA injection (1, 5, and 10 mg/kg, respectively) at 0–9 days after inoculation; e. H9N2 group, mice receiving H9N2 virus (105.5 TCID50) inoculation and cottonseed oil injection at 0–9 days after inoculation; fh. ATRA1 + H9N2-ATRA3 + H9N2 group, mice receiving H9N2 virus (105.5 TCID50) inoculation and ATRA injection (1, 5, and 10 mg/kg, respectively) at 0–9 days after inoculation. n = 5. ATRA, all-trans retinoic acid; TCID50, median tissue culture infective dose

Back to article page