Skip to main content

Table 2 Distribution of SCD patient by age group, sex, sickling genotype, and blood transfusion status against HCV detections at GICG, KBTH

From: Hepatitis C virus (HCV) infection among patients with sickle cell disease at the Korle-Bu teaching hospital

Characteristics No of patients
N (%)
HCV (Serology) HCV (RT-PCR)
Number of positives
n (%)
Odds ratio (95% confidence interval) P-value Number of positives
n (%)
Odds ratio (95% confidence interval) P-value
Overall total 141 (100) 12 (9)    8 (6)   
Gender       
Males 51 (36) 8 (16) 4.00 (1.1504–14.1029)
1
0.0290α 3 (6) 1.0625 (0.2432–4.6418)
1
1
Females 90 (64) 4 (4) 5 (6)
Age group (years)      
≤ 19 41 (29) 4 (10) 1.0811 (0.1819–6.4263) 0.9999 3 (7) 0.7895 (0.1218–5.1191) 0.9999
20–29 49 (35) 5 (10) 1.1628 (0.2075–6.5166) 1 1 (2) 0.4468 (0.0267–7.4900) 0.5329
30–39 22 (15) 2 (9) 1 1 1 (5) 1  
40–49 13 (9) 1 (8) 0.833 (0.0681–10.2021) 0.9999 1 (8) 0.833 (0.0681–10.2021) 0.9999
 ≥ 50 17 (12) 0 (0) * * 2 (12) * *
SCD type      
SS 88 (62) 7 (8) 0.8469 (0.2548–2.8153) 0.7664 5 (6) 1.0241 (0.2347–4.4685) 0.9999
SC 47 (33) 5 (11) 1.4966 (0.4485–4.9942) 0.5319 3 (6) 1.2273 (0.2805–5.3703) 0.9999
SD 4 (3) 0 (0) *   0 (0) *  
SF 2 (1) 0 (0) *   0 (0) *  
Blood transfusion      
Yes 72 (51) 4 (6) 0.4485 (0.1286–1.5640)
1
0.2377 2 (3) 0.3000 (0.0584–1.5646)
1
0.1599
No 69 (49) 8 (11)   6 (9)
  1. 1 indicates reference variable
  2. SS: Haemoglobin SS, SC: Haemoglobin SC, SD: Haemoglobin D-Punjab, SF: Fetal haemoglobin
  3. *Calculation not applicable due to no positive detected
  4. p-value set at < 0.05
  5. αSignificant finding