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Table 2 Distribution of SCD patient by age group, sex, sickling genotype, and blood transfusion status against HCV detections at GICG, KBTH

From: Hepatitis C virus (HCV) infection among patients with sickle cell disease at the Korle-Bu teaching hospital

Characteristics

No of patients

N (%)

HCV (Serology)

HCV (RT-PCR)

Number of positives

n (%)

Odds ratio (95% confidence interval)

P-value

Number of positives

n (%)

Odds ratio (95% confidence interval)

P-value

Overall total

141 (100)

12 (9)

  

8 (6)

  

Gender

      

Males

51 (36)

8 (16)

4.00 (1.1504–14.1029)

1

0.0290α

3 (6)

1.0625 (0.2432–4.6418)

1

1

Females

90 (64)

4 (4)

5 (6)

Age group (years)

     

≤ 19

41 (29)

4 (10)

1.0811 (0.1819–6.4263)

0.9999

3 (7)

0.7895 (0.1218–5.1191)

0.9999

20–29

49 (35)

5 (10)

1.1628 (0.2075–6.5166)

1

1 (2)

0.4468 (0.0267–7.4900)

0.5329

30–39

22 (15)

2 (9)

1

1

1 (5)

1

 

40–49

13 (9)

1 (8)

0.833 (0.0681–10.2021)

0.9999

1 (8)

0.833 (0.0681–10.2021)

0.9999

 ≥ 50

17 (12)

0 (0)

*

*

2 (12)

*

*

SCD type

     

SS

88 (62)

7 (8)

0.8469 (0.2548–2.8153)

0.7664

5 (6)

1.0241 (0.2347–4.4685)

0.9999

SC

47 (33)

5 (11)

1.4966 (0.4485–4.9942)

0.5319

3 (6)

1.2273 (0.2805–5.3703)

0.9999

SD

4 (3)

0 (0)

*

 

0 (0)

*

 

SF

2 (1)

0 (0)

*

 

0 (0)

*

 

Blood transfusion

     

Yes

72 (51)

4 (6)

0.4485 (0.1286–1.5640)

1

0.2377

2 (3)

0.3000 (0.0584–1.5646)

1

0.1599

No

69 (49)

8 (11)

 

6 (9)

  1. 1 indicates reference variable
  2. SS: Haemoglobin SS, SC: Haemoglobin SC, SD: Haemoglobin D-Punjab, SF: Fetal haemoglobin
  3. *Calculation not applicable due to no positive detected
  4. p-value set at < 0.05
  5. αSignificant finding