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Table 1 Estimated sequence and protein expression of the target gene

From: A novel cocktail therapy based on quintuplet combination of oncolytic herpes simplex virus-2 vectors armed with interleukin-12, interleukin-15, GM-CSF, PD1v, and IL-7 × CCL19 results in enhanced antitumor efficacy

Virus

Target gene (bp)

Protein expressed (pg/mL)

oHSV2-GM-CSF

1000

21,771.92 ± 934.50

oHSV2-IL12

2420

2281.78 ± 25.17

oHSV2-PD1v

1471

–

oHSV2-IL15

1910

224[16]

oHSV2-IL7 × CCL19

1511

1370.63 ± 20.38 (IL7); 2063.30 ± 98.13 (CCL19)

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Virology Journal

ISSN: 1743-422X