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Fig. 3 | Virology Journal

Fig. 3

From: A novel cocktail therapy based on quintuplet combination of oncolytic herpes simplex virus-2 vectors armed with interleukin-12, interleukin-15, GM-CSF, PD1v, and IL-7 × CCL19 results in enhanced antitumor efficacy

Fig. 3

Infectious and oncolytic activities of oHSV2-IL12, -PD1v, -IL15, -IL7 × CCL19, GM-CSF in vitro. A the recombinant viruses were used to infect tumor cell lines, containing B16R, A549, and CT26 at MOI = 1 for 48 h. Photographs were collected at 24 h and 48 h post-infection. B real-time xCELLigence cell analyzer was used to monitor the kinetics of tumor cell lysis induced by the recombinant viruses. Means of cell index from duplicate wells are presented. Data are representative of three experiments

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Virology Journal

ISSN: 1743-422X