Skip to main content

Table 4 Allele frequencies in COVID-19 patients and healthy controls

From: SNPs of ACE1 (rs4343) and ACE2 (rs2285666) genes are linked to SARS-CoV-2 infection but not with the severity of disease

SNP

Subjects (n)

Allele frequencies (%)

Pa

OR; 95% CI

Pc

OR; 95% CI

A

G

A2350G

Negative control (n = 50)

64 (64)

36 (36)

0.21

1.74; 0.73–4.17

0.007

2.1:1.2–3.5

Positive control (n = 35)

34 (48.6)

36 (51.4)

    

ICU patients (n = 44)

39 (44.3)

49 (55.7)

    

G8790A

Negative control (n = 50)

33 (33)

67 (67)

0.002

4.26; 1.7–10.65

0.0001

4.7; 2.4–9.2

Positive control (n = 35)

8 (11.4)

62 (88.6)

    

ICU patients (n = 44)

7 (8)

81 (92)

    
  1. Pa: adjusted P-value; Pc: P-value for Chi-Square test; OR: Odds ratio; CI: Confidence interval