Fig. 3

Dynamics of minority variants in sample pairs during A early HIV infection and B chronic HIV infection. (i) Some variants either increased in proportion between baseline and follow-up or remained at / above the detection limit of 5% (black solid line). (ii) Other variants decreased in proportion over time and were detected below 5% at follow-up. (iii) There were variants that increased in proportion over time to become majority variants and were thus maintained above 20% (black dotted line). (iv) Some minority variants that were detected at follow-up existed as majority variants at baseline. The median interval between baseline and follow-up sampling was 4 weeks (IQR: 3–8 weeks)