Fig. 4
From: Clinical and molecular aspects of human pegiviruses in the interaction host and infectious agent
Genome organization of hepaciviruses and pegiviruses. Coding region of a core (C) protein has not been identified for SPgV (GBV-A) or HPgV-1 (GBV-C). Hepegiviruses (HPgV-2/HHPgV-1) encode a protein named Y that is similar in properties and location to HCV & GBV-B. * The predicted sizes of the pore-forming ion channel proteins comparable to the HCV P7 are 21Â kDa for SPgV, 6Â kDa for HPgV-1 and 13Â kDa for GBV-B. The GBV-B 13Â kDa protein could be cleaved into P7 and P6 proteins, that the P7 protein, but not the P6 is essential for viability in vivo