Table 5 Nucleotide sequence mutations of HPV16 E6-E7 genes

NC001526

G

A

C

G

T

G

G

T

G

NC001526

A

A

G

C

T

C

T

T

MZ546266

G

1

MZ546295

G

T

C

C

1

MZ546267

A

A

2

MZ546296

A

T

2

MZ546268

G

2

MZ546297

G

T

C

2

MZ546269

2

MZ546298

T

2

MZ546270

G

1

MZ546299

T

1

MZ546271

2

MZ546300

A

T

2

MZ546272

1

MZ546301

T

C

1

MZ546273

A

A

1

MZ546302

A

1

MZ546274

A

G

A

1

MZ546303

A

1

MZ546275

A

1

MZ546304

C

1

MZ546276

G

A

G

1

MZ546305

C

1

MZ546277

T

1

MZ546306

C

1

MZ546278

C

2

MZ546307

2

Reference aa

K

R

T

D

D

E

R

L

R

N

N

E

S

L

R

C

S

aa position

1

2

3

3

3

4

9

4

2

2

3

6

6

7

9

9

4

5

9

2

2

6

6

0

2

9

9

5

3

7

7

4

5

aa mutations

G

S

N/Y

E

Q

Q

V

Q

H

S

F

C

Frequency

4

1

1

2

5

2

1

2

2

18

1

3

6

9

3

2

1

3

18