Table 3 Assays for SARS-CoV-2 antibody testing used in this study
From: Comparison of six antibody assays and two combination assays for COVID-19
Assay name (in this study) | Manufacturer (using instrument) | Measurement method | Target protein | Immunoglobulin class | FDA EUA | CE-IVD | |
|---|---|---|---|---|---|---|---|
1 | Elecsys Anti-SARS-CoV-2 (Elecsys) | Roche (Cobas e602) | ECLIA | N | Pan-Ig | (+) | (+) |
2 | SuperFlex™ Anti-SARS-CoV-2 Ab Assay (SuperFlex_Ab) | PerkinElmer (SuperFlex) | CLIA | S | Pan-Ig | (−) | (−) |
3 | SuperFlex™ Anti-SARS-CoV-2 IgM Assay (SuperFlex_IgM) | PerkinElmer (SuperFlex) | CLIA | N and S | IgM | (−) | (−) |
4 | SuperFlex™ Anti-SARS-CoV-2 IgG Assay (SuperFlex_IgG) | PerkinElmer (SuperFlex) | CLIA | S | IgG | (−) | (+) |
5 | iFlash-SARS-CoV-2 IgM (iFlash_IgM) | Shenzhen YHLO (iFlash 3000) | CLIA | N and (S) | IgM | (−) | (+) |
6 | iFlash-SARS-CoV-2 IgG (iFlash_IgG) | Shenzhen YHLO (iFlash 3000) | CLIA | N and (S) | IgG | (−) | (+) |