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Fig. 4 | Virology Journal

Fig. 4

From: The phosphatase and tensin homolog gene inserted between NP and P gene of recombinant Newcastle disease virus oncolytic effect test to glioblastoma cell and xenograft mouse model

Fig. 4

PTEN gene containing rNDV induces growth inhibition and cell death of T98G glioblastoma cells. A MTT assay of PTEN inserted rNDV Position “1” infected glioblastoma cell (T98G), PTEN inserted rNDV Position “2” infected glioblastoma cell (T98G), and rNDV infected glioblastoma cell (T98G). Significant differences are indicated as *p < 0.05. B Cytopathic effect (CPE) microscopic observation of glioblastoma cell (T98G) infected with PTEN inserted rNDV Position “1” (MOI 1), PTEN inserted rNDV Position “2” (MOI 1), rNDV (MOI 1), and not infected glioblastoma cell (T98G) (negative control). Scale bars, 100 μm

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