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Fig. 3 | Virology Journal

Fig. 3

From: The PB1 gene from H9N2 avian influenza virus showed high compatibility and increased mutation rate after reassorting with a human H1N1 influenza virus

Fig. 3

Virulence of reassortant viruses in mice. Virulence of the PB1-, PA- and NP-reassortant viruses was measured by infection of five mice, after which body-weight loss was measured for 14 days after infection. For reference, the human wt WSN-H1N1 and avian wt A2093-H9N2 viruses are shown. The body weight changes is plotted, and significant differences (Multiple t test with a = 0.05) are marked (*). The body weight changes are expressed as the mean with SD in each group (n = 5). #One mouse died on day 8, 9 and 11 d.p.i

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