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Fig. 1 | Virology Journal

Fig. 1

From: Upregulation of nuclear factor E2-related factor 2 (Nrf2) represses the replication of herpes simplex virus type 1

Fig. 1

HSV-1 infection induced oxidative stress and Nrf2 was activated in the early stage of HSV-1 infection. a HEp-2 cells were infected with HSV-1 at an MOI of 1 and samples were collected to identify the oxidative stress by 8-OHdG ELISA kit at 0, 6, 12 and 24 hpi. b The expression of Nrf2, Keap1, HO-1, NQO1 and virus protein ICP4 were identified by Western Blot. c The expression of Nrf2-ARE pathway protein was detected after infected with HSV-1 at different MOIs by Western Blot. Data represent the results from three independent experiments (Mean ± SD, ***P < 0.001, ns, not significant)

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Virology Journal

ISSN: 1743-422X