Table1 Socio-demographic and their associations with KSHV infection and HSV-2 infection in study participants

All subjects

16,501

Gender

 Male

7714(46.75)

1.00

1.00

1.00

1.00

 Female

8787(53.25)

0.93

(0.73,1.18)

0.95

(0.75,1.21)

1.77*

(1.63,1.92)

1.84*

(1.68,2.01)

 P

0.555

0.613

 < 0.001*

 < 0.001*

Age

 18–29 years

4238(25.68)

1.00

1.00

1.00

1.00

 30–39 years

3333(20.20)

1.18

(0.76,1.82)

1.23

(0.79,1.90)

2.26*

(2.01,2.55)

2.48*

(2.19,2.81)

 40–49 years

2588(15.68)

1.58*

(1.02,2.43)

1.67*

(1.08,2.57)

2.41*

(2.13,2.73)

2.92*

(2.56,3.33)

 50–59 years

1869(11.33)

1.87*

(1.17,2.95)

2.16*

(1.35,3.43)

2.11*

(1.79,2.49)

3.07*

(2.57,3.66)

60–80 years

4473(27.11)

2.86*

(2.02,4.14)

3.37*

(2.36,4.90)

2.45*

(2.16,2.77)

3.81*

(3.32,4.38)

 P

 < 0.001*

 < 0.001*

 < 0.001*

 < 0.001*

Race/ethnicity

 Non-Hispanic white

6318(38.29)

1.00

1.00

1.00

1.00

 Non-Hispanic black

4840(29.33)

1.29

(0.95,1.75)

1.59*

(1.17,2.17)

4.32*

(3.89,4.81)

5.52*

(4.92,6.19)

 Mexican–American

4664(28.26)

1.52*

(1.13,2.05)

1.96*

(1.44,2.66)

1.58*

(1.41,1.77)

2.00*

(1.78,2.25)

 Other

679(4.11)

1.20

(0.62,2.13)

1.42

(0.73,2.52)

1.77*

(1.40,2.23)

2.16*

(1.69,2.74)

 P

0.017*

 < 0.001*

 < 0.001*

 < 0.001*

Household size

 1–4

12,230(74.12)

1.00

1.00

1.00

1.00

 5–9

3875(23.48)

0.90

(0.66,1.19)

0.99

(0.72,1.35)

0.98

(0.89,1.07)

0.96

(0.86,1.06)

  ≥ 10

396(2.40)

1.07

(0.45,2.13)

1.15

(0.48,2.34)

0.95

(0.73,1.23)

1.03

(0.77,1.36)

 P

0.619

0.741

0.562

0.771

Education

 0 years

424(2.59)

1.00

1.00

1.00

1.00

 1–12 years

11,328(69.09)

0.30*

(0.19,0.49)

0.46*

(0.28,0.79)

0.76

(0.58,1.00)

0.84

(0.63,1.13)

 ≥ 13 years

4645(28.33)

0.21*

(0.13,0.36)

0.39*

(0.22,0.70)

0.53*

(0.40,0.71)

0.64*

(0.47,0.87)

 P

 < 0.001*

0.005*

 < 0.001*

 < 0.001*

Poverty income ratio

  ≤ 1.3

4987(33.36)

1.00

1.00

1.00

1.00

 1.3—3.5

6589(44.08)

0.71*

(0.54,0.95)

0.73*

(0.55,0.98)

0.72*

(0.65,0.79)

0.79*

(0.71,0.88)

  > 3.5

3371(22.55)

0.60*

(0.42,0.86)

0.65*

(0.43,0.95)

0.52*

(0.46,0.59)

0.65*

(0.57,0.75)

 P

0.003*

0.005*

 < 0.001*

 < 0.001*

Occupation

 Unemployment

6744(40.88)

1.00

1.00

1.00

1.00

 Employment

9754(59.12)

0.65*

(0.51,0.83)

0.92

(0.69,1.22)

0.76*

(0.70,0.83)

0.97

(0.87,1.07)

 P

 < 0.001*

0.358

 < 0.001*

0.278

Marital status

 Never married

3337(20.26)

1.00

1.00

1.00

1.00

 Married/living as married

9950(60.42)

1.07

(0.77,1.50)

0.69

(0.47,1.02)

1.00

(0.90,1.11)

0.96

(0.86,1.08)

 Separated/divorced/widowed

3182(19.32)

1.70*

(1.18,2.47)

0.93

(0.61,1.45)

0.96

(0.84,1.08)

0.93

(0.81,1.06)

 P

0.003*

0.781

0.478

0.346

Smoking status

 No-smoking

8209(49.75)

1.00

1.00

1.00

1.00

 On-smoking

4438(26.90)

1.13

(0.83,1.52)

1.21

(0.88,1.65)

1.47*

(1.33,1.61)

1.71*

(1.53,1.90)

 Quit-smoking

3853(23.35)

1.67*

(1.26,2.21)

1.44*

(1.06,1.95)

1.20*

(1.08,1.34)

1.41*

(1.24,1.59)

 P

 < 0.001*

0.023*

 < 0.001*

 < 0.001*

Drinking status

 No-drinking

2838(17.98)

1.00

1.00

1.00

1.00

 Drinking

12,943(82.02)

0.87

(0.65,1.19)

1.07

(0.77,1.47)

1.11

(1.00,1.24)

1.54*

(1.36,1.75)

 P

0.369

0.602

0.062

 < 0.001*