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Table 1 Proviral HIV integration sites in the PBMC of the kidney (A) and liver (B) recipients during the post-transplant period

From: Analysis of HIV quasispecies and virological outcome of an HIV D+/R+ kidney–liver transplantation

Integration site (chromosome; position)

% of matches

  
 

09/13/2019

02/07/2020

01/22/2021

A

   

NC_000015.10; 77401646

39.74

0

0

NC_000010.11; 21714841

29.23

0

0

NC_000005.10; 139967566

18.24

54.04

57.10

NC_000001.11; 226567704

3.04

0.11

0.20

NC_000002.12; 16097405

1.51

3.34

3.61

NC_000013.11; 59598085

1.28

0

9.37

NC_000011.10; 133588835

1.23

0

0

NC_000020.11; 56101682

0.37

0

0

NC_000013.11; 28414033

0.26

0

0

NC_000014.9; 52551000

0.24

0.54

0.41

NC_000020.11; 49687838

0.24

0.81

1.09

NC_000022.11; 46086683

0.15

0

0

NC_000004.12; 35007318

0.13

0

0

NC_000009.12; 122992409

0.05

0.54

0.08

NC_000009.12; 74259647

0

28.09

0

NC_000018.10; 36235516

0

1.35

0

NC_000004.12; 35007318

0

0.97

0.73

NC_000011.10; 58541534

0

0.81

0

NC_000007.14; 45947801

0

0.70

0

NC_000016.10; 5408445

0

0.48

0

NC_000016.10; 72345482

0

0.43

0

NC_000003.12; 163832295

0

0

9.61

NC_000001.11; 26998745

0

0

1.42

NC_000022.11; 46086683

0

0

0.93

NC_000017.11; 17716854

0

0

0.53

NC_000001.11; 196452109

0

0

0.45

NC_000016.10; 5408445

0

0

0.41

NC_000005.10; 140366572

0

0

0.41

NC_000001.11; 240464202

0

0

0.32

Integration site (chromosome; position)

% of matches

  
 

09/23/2019

02/15/2020

 

B

   

NC_000005.10; 139967566

87.96

87.64

 

NC_000002.12; 16097405

4.31

4.53

 

NC_000020.11; 49687838

1.62

1.65

 

NC_000014.9; 52551000

1.26

0.82

 

NC_000004.12; 35007318

1.17

1.03

 
  1. The integration sites are reported as human chromosome position; the frequencies for each integration site and for each time point evaluated were calculated as number of reads matched on that site, divided the number of total reads containing a LTR sequence obtained from that sample (% of matches). Only frequencies deriving from at least 8 matches were considered