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Table 4 Nucleotide mutation and amino acid substitution in HPV-52 E6

From: The polymorphism analysis and epitope predicted of Alphapapillomavirus 9 E6 in Sichuan, China

 

HPV-52 E6

No

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

20

21

Location

61

82

93

118

136

136

230

237

249

255

265

270

277

277

278

315

315

366

381

412

429

Mutation

G–A

C–T

G–C

A–C

C–G

C–T

G–A

T–C

G–T

G–A

G–A

G–A

A–C

A–G

A–G

T–G

T–A

C–A

T–A

G–A

A–G

Frequency (%)

0.70

0.70

0.70

0.70

0.70

2.10

0.70

0.70

85.40

9.70

0.70

0.70

1.40

2.10

84.00

0.70

0.70

0.70

0.70

0.70

2.80

Substitution

E21K

–

–

–

L46V

L46V

R77K

–

–

–

E89K

–

K93R

K93R

K93R

I105M

I105M

N122K

N127I

E138K

–

  1. Compared with the HPV-52 E6 reference sequence (NC001592), the mutations are marked with the corresponding bases and amino acid, and those without changes are replaced with a dash (–). No. means the number of nucleotide mutations, Location means the sites of nucleotide mutations, Mutation means the style of nucleotide mutations, Frequency (%) means the percentage of nucleotide mutations, Substitution means the amino acid substitution that occurred by nucleotide mutations